Construction of an artificial recombinant bicistronic plasmid DNA vaccine against porcine rotavirus
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چکیده
منابع مشابه
Construction of an artificial recombinant bicistronic plasmid DNA vaccine against porcine rotavirus.
The attenuated Salmonella typhimurium χ4550 strain was used to harbour a reconstructed bicistronic DNA vaccine against porcine rotavirus, which carried the rotavirus nonstructural protein 4 (NSP4) and VP7 genes simultaneously. Using a balanced lethal system, the kanamycin resistance gene of expressing eukaryotic plasmids pVAX1 and pVAXD were replaced by the aspartate β-semialdehyde dehydrogenas...
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ژورنال
عنوان ژورنال: Onderstepoort J Vet Res
سال: 2013
ISSN: 2219-0635,0030-2465
DOI: 10.4102/ojvr.v80i1.498